Diazepam Injection - British Pharmacopoeia ». Holzgrabe, « Emerging Antimicrobial Drug Resistance in Africa and Latin America: Search for Reasons », Risk Manag Healthc Policy, vol. GPHF | GPHF-MinilabTM: Main manual now updated and extended ». Produits médicaux de qualité inférieure ou falsifiés ». of Medicine, Causes of Falsified and Substandard Drugs. Committee on Understanding the Global Public Health Implications of Substandard, B. Dans les pays en développement, 1 médicament sur 10 est de qualité inférieure ou falsifié ». Analytical methods for determination of benzodiazepines. Al-Areqi, « Spectrophotometric Determination of Diazepam in Pharmaceutical Forms by Ion-Pairing with Ferrithiocyanide Complex », Science Journal of Analytical Chemistry, vol. Ortiz, « Analysis of multicomponent formulations containing phenylpropanolamine hydrochloride, caffeine and diazepam by using LC », J Pharm Biomed Anal, vol. Benzodiazepines Revisited | British Journal of Medical Practitioners ». Bokonji, « The Influence of Diazepam on Atropine Reversal of Behavioural Impairment in Dichlorvos-Treated Rats », Pharmacology & Toxicology, vol. ALCOHOL WITHDRAWAL TREATMENT IN INTOXICATED VS NON-INTOXICATED PATIENTS: A CONTROLLED OPEN-LABEL STUDY WITH TIAPRIDE/CARBAMAZEPINE, CLOMETHIAZOLE AND DIAZEPAM | Alcohol and Alcoholism | Oxford Academic ». Wang, « The binding of -diazepam to guinea-pig ileal longitudinal muscle and the in vitro inhibition of contraction by benzodiazepines », Br J Pharmacol, vol. We also found that all samples were unregistered.Ĭonclusion: The results clearly raise the issue of registration of drugs before their market authorization and the importance of continuous quality control and post-marketing drug analysis to ensure health and guarantee access to quality medicines for the health and well-being of populations. Non-compliant drugs were mainly from the public sector. Results: A total of 44 samples were analyzed according to a risk-based protocol, of which 32 were compliant with a rate of 91% against 12 non-compliant or 9% (P≤0,05). The selection of drugs and geographic areas was made using risk-based sampling using the Drug Risk Assessment Tool (MedRS) developed by USP / PQM +. It aimed to assess the quality of Diazepam injection available on the market. Methods: The survey covered certain regions and certain points of sale.
Drug Post-Marketing Surveillance (PMS) therefore plays an important role in detecting poor quality products on the market. Objectives: In a world marked by the increase in chemoresistance leading to the adoption of therapeutic combinations, the advent of generic multi-source drugs, the spread of counterfeiting and substandard drugs, often without active ingredients or falsified active ingredients, a Greater vigilance by pharmaceutical regulatory authorities is needed.
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